2-Chloro-7-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-7H-purin-6-amine

Chemical Name:2-Chloro-7-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-7H-purin-6-amine
CAS Number:174462-88-5
Molecular Formula:C₁₀H₁₁ClFN₅O₃
Molecular Weight:303.68
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-Chloro-7-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-7H-purin-6-amine, is a derivative of Clofarabine (C586890), a second generation purine nucleoside analog; antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic.
References:Gandhi, V., et al.: Clin. Cancer Res., 9, 6335 (2003), Kantarjian, H., et al.: Blood, 102, 2379 (2003), Faderl, S., et al.: Cancer, 103, 1985 (2005),
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