2-Cyclohexyl-1-(5H-imidazo[5,1-a]isoindol-5-yl)ethanoned-d11

Chemical Name:2-Cyclohexyl-1-(5H-imidazo[5,1-a]isoindol-5-yl)ethanoned-d11
Molecular Formula:C₁₈H₉D₁₁N₂O
Molecular Weight:291.43
Category:Building Blocks; Isotopic Labeled Analogues;
Applications:2-Cyclohexyl-1-(5H-imidazo[5,1-a]isoindol-5-yl)ethanoned-d11 is an intermediate in synthesizing NLG919-d10 (N630002). It is a isotope labelled analog of NLG919 (N630000). NLG919 is a potent indoleamine-2,3-dioxygenase (IDO) pathway inhibitor and is suitable for the treatment of immunosuppression associated with cancer.
References:Mautino, M.R., et al.: Cancer Res., 73, no pp. (2013); Li, M., et al.: J. Immunother. Cancer, 2, no pp. (2014)
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