2′-Ethyl Simvastatin-d6

Chemical Name:2′-Ethyl Simvastatin-d6
Synonyms:2-Methylpropanoic Acid [1S-[1α,3α,7β,8β(2S*,4S*),8aβ]]-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester-d6;
Alternate CAS #:Unlabelled: 79902-42-4
Molecular Formula:C₂₃H₂₈D₆O₅
Molecular Weight:396.55
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Isotope labelled 2′-Ethyl Simvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
References:Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986),
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