2-Hydroxymelatonin Glucuronide

Chemical Name:2-Hydroxymelatonin Glucuronide
Synonyms:(2S,3S,4S,5R)-6-((3-(2-Acetamidoethyl)-5-methoxy-1H-indol-2-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid
Molecular Formula:C₁₉H₂₄N₂O₉
Molecular Weight:424.4
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-Hydroxymelatonin Glucuronide is impurity of 2-Hydroxymelatonin (H944630). 2-Hydroxymelatonin, is a metabolite of Melatonin (M215000), which is a hormone found in animals, plants, and microbes. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.
References:Huether, G., et al.: Life Sci., 51, 945
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