2,5-Dihydro-2,5-dioxo-β-sulfo-1H-pyrrole-1-butanoic Acid 1-(2,5-Dioxo-1-pyrrolidinyl) Ester

Chemical Name:2,5-Dihydro-2,5-dioxo-β-sulfo-1H-pyrrole-1-butanoic Acid 1-(2,5-Dioxo-1-pyrrolidinyl) Ester
Synonyms:Succinimidyl 4-N-Maleimido-3-sulfo-butyrate;
CAS Number:1193111-53-3
Molecular Formula:C₁₂H₁₂N₂O₉S
Molecular Weight:360.3
Category:Research Tools; Miscellaneous; Molecular Biology; Cross-linkers;
Applications:2,5-Dihydro-2,5-dioxo-β-sulfo-1H-pyrrole-1-butanoic Acid 1-(2,5-Dioxo-1-pyrrolidinyl) Ester is used in the synthesis of hydrophilic heterobifunctional crosslinkers for conjugation of antibodies with highly cytotoxic agents.
References:Zhao, R. Y., et al.: J. Med. Chem., 54, 3606-3623 (2011)
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