[(25R)-3α,7α-Dihydroxy-5β-cholestan-26-oyl]taurine-d4 Sodium Salt

Chemical Name:[(25R)-3α,7α-Dihydroxy-5β-cholestan-26-oyl]taurine-d4 Sodium Salt
Alternate CAS #:Unlabelled Free Base: 120202-00-8
Molecular Formula:C₂₉H₄₆D₄NNaO₆S
Molecular Weight:567.79
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
Applications:[(25R)-3α,7α-Dihydroxy-5β-cholestan-26-oyl]taurine-d4 Sodium Salt is the labeled deuterium form of [(25R)-3α,7α-Dihydroxy-5β-cholestan-26-oyl]taurine Sodium Salt (D452630) that is derived from Chenodeoxycholic Acid (C291900), which is a major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Facilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol.
References:Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972), Iser, J.H., et al.: Drugs, 21, 90 (1981), Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986)
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