28-Ethylhydroxy Everolimus-d4 Impurity

Chemical Name:28-Ethylhydroxy Everolimus-d4 Impurity
Molecular Formula:C₅₅H₈₃D₄NO₁₅
Molecular Weight:1006.3
Category:Standards; Isotopic Labeled Analogues;
Applications:28-Ethylhydroxy Everolimus-d4 Impurity is a deuterium labelled 28-Ethylhydroxy-everolimus Impurity (E945435). It is also an impurity of Everolimus (E945400), which is a derivative of Rapamycin (R124000).  Everolimus inhibits cytokine-mediated lymphocyte proliferation.
References:Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)
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