(2R,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane

Chemical Name:(2R,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane
Synonyms:(2R)-6-Fluoro-3,4-dihydro-2-(2R)-oxiranyl-2H-1-benzopyran;[R-(R*,R*)]-6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran;(2R)-2-((2R)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)oxirane; (2R)​-6-​Fluoro-​3,​4-​dihydro-​2-​[(2R)​-​2-​oxiranyl]​-​2H-​1-​benzopyran
CAS Number:197706-50-6
Molecular Formula:C₁₁H₁₁FO₂
Molecular Weight:194.2
Category:Building Blocks; Miscellaneous;
Applications:(2R,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane is an intermediate to synthesize Nebivolol (rac, HCl salt, N387900) which is a β1-Adrenergic blocker.
References:Van de Water, A., et al.: J. Cardiovasc. Pharmacol., 11, 552 (1988), De Cree, J., et al.: Angiology, 41, 95 (1990)
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