(2R,3S)-β-Hydroxyleucine

Chemical Name:(2R,3S)-β-Hydroxyleucine
Synonyms:threo-3-Hydroxy-D-leucine; (2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid; D-threo-β-Hydroxyleucine; (3S)-3-Hydroxy-D-leucine;
CAS Number:87421-23-6
Molecular Formula:C₆H₁₃NO₃
Molecular Weight:147.17
Category:Research Tools;
Applications:(2R,3S)-β-Hydroxyleucine is a nonprotein amino acid. (2R,3S)-β-Hydroxyleucineis an inhibitor of serine protease. In particular, (2R,3S)-β-Hydroxyleucine was effective in inhibiting trypsin and proteinase K of the serine proteases group. (2R,3S)-β-Hydroxyleucine was not able to inhibit the growth of gram-positive and gram-negative bacteria and yeasts unlike its (2S,3R)-isomer.
References:Hovhannisyan, N. et al.: Amino Acids, 37, 531 (2009); Chitchyan, M.B. et al.: Hayas. Kensab. Hand., 59, 248 (2007);
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