3-(1-Hydroxybutyl)-3a,4-dihydroisobenzofuran-1(3H)-one

Chemical Name:3-(1-Hydroxybutyl)-3a,4-dihydroisobenzofuran-1(3H)-one
Molecular Formula:C₁₂H₁₆O₃
Molecular Weight:208.25
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Natural Products;
Applications:3-(1-Hydroxybutyl)-3a,4-dihydroisobenzofuran-1(3H)-one is an intermediate for the synthesis of Ligustilide (L397900), which is a dihydrophthalide, and an active ingredients of umbelliferous plants as Angelica sinensis and Ligusticum chuanxiong, having wide range of pharmacology effects on neuroprotection, vasodilatation, anti-caner and anti-tumor, analgesia and anti-inflammation.
References:Zuo, A., et al.: Zhongguo Zhongyao Zazhi, 37, 3350 (2012); Long, R., et al.: Tropical J. Pharmac. Res., 11, 421 (2012);
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