3-(1H-Imidazol-4-yl)propyl (4-bromophenethyl)carbamimidothioate Dihydrobromide

Chemical Name:3-(1H-Imidazol-4-yl)propyl (4-bromophenethyl)carbamimidothioate Dihydrobromide
CAS Number:145196-90-3
Molecular Formula:C₁₅H₂₁Br₃N₄S
Molecular Weight:529.1
Category:Building Blocks; Miscellaneous;
Applications:3-(1H-Imidazol-4-yl)propyl (4-bromophenethyl)carbamimidothioate Dihydrobromide can be useful in the preparation of S-alkyl-N-alkylisothioureas via adddition of primary amines to acyl isothiocyanates, S-alkylation and hydrazinolysis and its application to the synthesis of histamine H3 antagonist clobenpropit and its analogs.
References:Yoneyama, H., et al.: J. Org. Chem., 73, 2096 (2008)
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