3-Bromo-vortioxetine Hydrobromide

Chemical Name:3-Bromo-vortioxetine Hydrobromide
Synonyms:1-(2-((3-Bromo-2,4-dimethylphenyl)thio)phenyl)piperazine Hydrobromide;
Molecular Formula:C₁₈H₂₁BrN₂S • HBr
Molecular Weight:377.34 + (80.91)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-Bromo-vortioxetine Hydrobromide is an impurity of the drug Vortioxetine (V766000), which is a multimodal serotonergic agent. It inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptors and SERT.
References:Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013);
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