3-Deamino 3-Hydroxy Linagliptin-d3

Chemical Name:3-Deamino 3-Hydroxy Linagliptin-d3
Synonyms:(S)-7-(But-2-yn-1-yl)-8-(3-hydroxypiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione-d3;
Alternate CAS #:S-Isomer – 1620278-39-8 – Unlabelled
Molecular Formula:C₂₅H₂₄D₃N₇O₃
Molecular Weight:476.55
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Isotope labelled 3-Deamino 3-Hydroxy Linagliptin is an impurity in the synthesis of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.
References:Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);
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