(3S)-2-(2,2-Diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinolinecarboxylic Acid Sodium Salt Dihydrate

Chemical Name:(3S)-2-(2,2-Diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinolinecarboxylic Acid Sodium Salt Dihydrate
Synonyms:(S)-5-(Benzyloxy)-2-(2,2-diphenylacetyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid Sodium Salt Dihydrate
CAS Number:1356460-29-1
Alternate CAS #:Free acid: 1316755-16-4
Molecular Formula:C₃₂H₃₃NNaO₇
Molecular Weight:566.6
Category:Building Blocks; Miscellaneous;
Applications:(3S)-2-(2,2-Diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinolinecarboxylic Acid Sodium Salt Dihydrate is a derivative of (3S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic Acid (T293190, HCl); an intermediate in the synthesis of Moexipril (M485350, HCl) which is an angiotensin converting enzyme (ACE) inhibitor.
References:Klutchko, S., et al.: J. Med. Chem., 29, 1953 (1986); Edling, O., et al.: J. Pharmacol. Exp. Ther., 275, 854 (1995); White, W.B., et al.: J. Hum. Hypertens., 8, 917 (1994); Stimpel, M., et al.: Cardiology 87, 313 (1996)
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