4-((4-(7-Chloroquinolin-4-yl)piperazin-1-yl)sulfonyl)benzene-1,3-diamine

Chemical Name:4-((4-(7-Chloroquinolin-4-yl)piperazin-1-yl)sulfonyl)benzene-1,3-diamine
Synonyms:VR23 Relative Compound 2
Alternate CAS #:1624602-30-7
Molecular Formula:C₁₉H₂₀ClN₅O₂S
Molecular Weight:417.91
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-((4-(7-Chloroquinolin-4-yl)piperazin-1-yl)sulfonyl)benzene-1,3-diamine is a VR23 (V767023) related compound. VR23 is a quinoline-sulfonyl hybrid proteasome inhibitor which is used in cancer therapeutics. Targets cancer via cycline E-mediated centrosome.
References:Pundir, S. et al.: Canc. Res., 75, 4164 (2015);
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