4-​(4-​Fluorophenyl)​-​5-​methoxy-​2,​6-​bis(1-​methylethyl)​-3-pyridinemethanol

Chemical Name:4-​(4-​Fluorophenyl)​-​5-​methoxy-​2,​6-​bis(1-​methylethyl)​-3-pyridinemethanol
Molecular Formula:C₁₉H₂₄FNO₂
Molecular Weight:317.4
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-​(4-​Fluorophenyl)​-​5-​methoxy-​2,​6-​bis(1-​methylethyl)​-3-pyridinemethanol is an intermediate in the synthesis of Cerivastatin Sodium Salt (C277000), which is a competitive inhibitor of HMG-CoA reductase.
References:Ness, C.G., et al.: Arch. Biochem. Biophys., 325, 242 (1996), Steinke, W., et al.: Japan. Pharmacol. Ther., 24, Suppl. 9, S1217 (1996),
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