4-[5-(Difluoromethyl)-3-phenyl-4-isoxazolyl]benzenesulfonamide

Chemical Name:4-[5-(Difluoromethyl)-3-phenyl-4-isoxazolyl]benzenesulfonamide
Synonyms:SC 791; 4-(5-(Difluoromethyl)-3-phenylisoxazol-4-yl)benzenesulfonamide
CAS Number:181696-33-3
Molecular Formula:C₁₆H₁₂F₂N₂O₃S
Molecular Weight:350.34
Category:Standards; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:4-[5-(Difluoromethyl)-3-phenyl-4-isoxazolyl]benzenesulfonamide is a COX-​2 inhibitor which has been shown to modifiy voltage gated potassium 2.1 channel gating and, at high concentrations, induce some immunomodulatory effects.
References:Frolov, R. V., et al.: Brain Res., 1359, 67 (2010); Furst, S. M., et al.: J. Immunotoxicol., 2, 161 (2005)
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