4-Amino-N-((2R,3S)-3-amino-2-(3-(3R,3aS,6aR)-hexahydro-furo[2,3-b]furanyl)oxycarbonyloxy-4-phenylbutyl)-N-(isobutyl)benzene Sulfonamide

Chemical Name:4-Amino-N-((2R,3S)-3-amino-2-(3-(3R,3aS,6aR)-hexahydro-furo[2,3-b]furanyl)oxycarbonyloxy-4-phenylbutyl)-N-(isobutyl)benzene Sulfonamide
Molecular Formula:C₂₇H₃₇N₃O₇S
Molecular Weight:547.66
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Amino-N-((2R,3S)-3-amino-2-(3-(3R,3aS,6aR)-hexahydro-furo[2,3-b]furanyl)oxycarbonyloxy-4-phenylbutyl)-N-(isobutyl)benzene Sulfonamide is derived from Benzyl ((2S,3R)-3-Hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamate (B279925), which can be used as reactant/reagent in synthetic preparation of peptide-like compounds as HIV-1 protease inhibitors.Also, it is an impurity of Amprenavir (A634400), which is a selective HIV protease inhibitor. An analogue of Ritonavir.
References:Yang, M., et al.: Faming Zhuanli Shenqing, CN 101260073 A 20080910 (2008); Adkins, J.C., et al.: Drugs, 55, 837 (1998)
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