4-Deschloro 4-Ethoxy Melphalan Dihydrochloride

Chemical Name:4-Deschloro 4-Ethoxy Melphalan Dihydrochloride
Synonyms:(S)-2-Amino-3-(4-((2-chloroethyl)(2-ethoxyethyl)amino)phenyl)propanoic Acid Dihydrochloride
Molecular Formula:C₁₃H₁₈Cl₂N₂O₂ • 2(HCl)
Molecular Weight:305.20 + 2(36.46)
Category:Standards; Amino Acids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Deschloro 4-Ethoxy Melphalan Dihydrochloride is an impurity of Melphalan (M216900), a nitrogen mustard analogue that is used as a chemotherapeutic agent for various types of cancers (such as multiple myeloma and plasma-cell leukemia).
References:Efthimiou, M., et al.: Mutat. Res. Fund. Mol. Mech. Mut., 617, 125 (2007); McElwain, T. & Powles, R.: Lancet, 322, 822 (1983); San Miguel, J., et al.: New Engl. J. Med., 359, 906 (2008)
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