4-Desmethyl Istradefylline

Chemical Name:4-Desmethyl Istradefylline
Synonyms:(E)-1,3-Diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-1H-purine-2,6-dione
CAS Number:160434-48-0
Molecular Formula:C₁₉H₂₂N₄O₄
Molecular Weight:370.4
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Desmethyl Istradefylline is an impurity of Istradefylline (I927000), a selective A(2A) antagonist used in the treatment of Parkinson’s disease. 4-Desmethyl Istradefylline have also been shown to exhibit inhibitory potency towards adenosine A2A receptors and is classified as its an adenosine A2A receptor antagonist.
References:Jorg, M., et al.: Bioorg. Med. Chem. Lett., 23, 3427 (2013);
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Taskcm is committed to providing cost-effective products that facilitate drug delivery with our customers.