4-Ethoxy-3-(4-pyridinyl)-3-buten-2-one

Chemical Name:4-Ethoxy-3-(4-pyridinyl)-3-buten-2-one
Synonyms:(E)-4-Ethoxy-3-(pyridin-4-yl)but-3-en-2-one; Milrinone Impurity 11
Impurity
Milrinone Impurity 11
CAS Number:88349-61-5
Molecular Formula:C₁₁H₁₃NO₂
Molecular Weight:191.23
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Ethoxy-3-(4-pyridinyl)-3-buten-2-one (Milrinone Impurity 11) is an impurity of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Cardiotonic.
References:Hagen, V., et. al.: Pharmazie, 44, 809 (1989); Alousi, A.A., et al.: J. Cardiovasc Pharmacol., 5, 792 (1983); Maskin, C.S., et al.: Circulation, 67, 1065 (1983); Sinoway, L.S., et al.: J. Am. Coll. Cardiol., 2, 327 (1983); Baim, D.S., et al.: N. Engl. J. Med., 309, 748 (1983)
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