4-Ethynyl-2-oxazolidinone

4-Ethynyl-2-oxazolidinone

Chemical Name:4-Ethynyl-2-oxazolidinone
CAS Number:1087043-50-2
Molecular Formula:111.10
Molecular Weight:111.1
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Ethynyl-2-oxazolidinone is derived from 3-Butyn-1-ol (B809750), which is an unsaturated alcohol that is used as a reagent to synthesize Kainic acid (K135000), a neuroexcitatory and neurotoxic analogue of glutamate that is utilized as a means to selectively lesion neuronal cell bodies. 3-Butyn-1-ol is also an important intermediate to prepare a variety of natural products in food and cosmetic industries.
References:Anderson, J. & Whiting, M.: J. Org. Chem., 68, 6160 (2003); Ben-Ari, Y., et al.: Brain Res., 165, 3362 (1979); Olney, J., et al.: Brain Res., 77, 507 (1974); Yu, X., et al.: Org. Prep. Proc. Int., 38, 467 (2006)
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