4,4′-(((Carbonylbis(azanediyl))bis(3-chloro-4,1-phenylene))bis(oxy))bis(7-methoxyquinoline-6-carboxamide)

Chemical Name:4,4′-(((Carbonylbis(azanediyl))bis(3-chloro-4,1-phenylene))bis(oxy))bis(7-methoxyquinoline-6-carboxamide)
Molecular Formula:C₃₅H₂₆Cl₂N₆O₇
Molecular Weight:713.52
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4,4′-(((Carbonylbis(azanediyl)) bis (3-chloro-4,1-phenylene))bis(oxy))bis(7-methoxyquinoline-6-carboxamide) is related to Lenvatinib (L329400) an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.
References:Matsui, J., et al.: Clin. Cancer Res., 14, 5459 (2008); Gild, M., et al.: Nature Rev. Endocrinol., 7, 617 (2011)
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