5’-Amino-fluorescein Mycophenolate β-D-Glucuronide

Chemical Name:5’-Amino-fluorescein Mycophenolate β-D-Glucuronide
Synonyms:Mycophenolic Acid β-D-Glucuronide Fluoresceinamine; (2S,3S,4S,5R,6S)-6-((5-((E)-6-((3′,6′-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthen]-5-yl)amino)-3-methyl-6-oxohex-2-en-1-yl)-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-4-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid
Molecular Formula:C₄₃H₃₉NO₁₆
Molecular Weight:825.77
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5’-Amino-fluorescein Mycophenolate β-D-Glucuronide is a derivative of Mycophenolic Acid β-D-Glucuronide(M831520). Mycophenolic Acid β-D-Glucuronide is a metabolite of Mycophenolic Acid (M831500), an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
References:Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),
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