5-Androsten-3a,17a-diol 17-sulfate Sodium

Chemical Name:5-Androsten-3a,17a-diol 17-sulfate Sodium
Synonyms:(3R,8R,9S,10S,13S,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl sulfate Sodium
Molecular Formula:C₁₉H₃₁NaO₅S
Molecular Weight:394.5
Applications:5-Androsten-3a,17a-diol 17-sulfate is a derivative of Pregnenolone(P712200) which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus. It is a modulator of cytochrome P 450-3A.
References:Bjondahl, K., et al.: Med. Biol., 54, 454 (1976), Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001), Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002), Abe, C., et al.: Lipids, 42, 637 (2007),
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