5-Bromo-3-methylpyridazine

5-Bromo-3-methylpyridazine

Chemical Name:5-Bromo-3-methylpyridazine
Synonyms:5-Bromo-3-methyl-pyridazine
Molecular Formula:C₅H₅BrN₂
Molecular Weight:173.01
Category:Building Blocks; Miscellaneous;
Applications:5-Bromo-3-methylpyridazine is synthesized from 1,2,4-Triazol-4-amine (T767420), which is an intermediate used to prepare potent, selective, and orally active cyclooxygenase-​2 inhibitors. It is also used to synthesize hydroxyphenacyl azoles and related azolium derivatives as antifungal agents.
References:Song, Y., et al.: J. Med. Chem., 42, 1151 (1999); Emami, S., et al.: Bioorg. Med. Chem. Lett., 18. 141 (2008)
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