Chemical Name:5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl Acetate
Molecular Formula:C₁₅H₂₀BFO₄
Molecular Weight:294.13
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl Acetate, is an impurity of Crisaborole, a nonsteroidal topical medication approved for the treatment of mild-to-moderate atopic dermatitis in patients 2 years of age and older.
References:FDA Approves Eucrisa for Eczema”. U.S. Food and Drug Administration. 14 December 2016; Nazarian, R; et al,: Current Opinion in Investigational Drugs. 10 (11): 1236–42.
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5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl Acetate
