6’-Hydroxymethyl Lovastatin Sodium Salt

Chemical Name:6’-Hydroxymethyl Lovastatin Sodium Salt
Synonyms:[1S-[1α(βS*,δS*),2α,6α,8β(R*),8aα]]-1,2,6,7,8,8a-Hexahydro-β,δ-dihydroxy-6-(hydroxymethyl)-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid Sodium Salt;
Alternate CAS #:Free Acid: 114801-34-2
Molecular Formula:C₂₄H₃₇NaO₇
Molecular Weight:460.54
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:6’-Hydroxymethyl Lovastatin Sodium Salt, is a metabolite of Lovastatin (L472225), which is used in combination with diet, weight-loss, and exercise for lowering cholesterol. It is also a fungal metabolite, which is a potent inhibitor of HMG-CoA reductase.
References:Bilheimer, D.W., et al.: Proc. Nat. Acad. Sci. USA, 80, 4124 (1983),
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