(6R,7R)-7-Amino-3-((1-methylpyrrolidin-1-ium-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate-d8 Hydrochloride

Chemical Name:(6R,7R)-7-Amino-3-((1-methylpyrrolidin-1-ium-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate-d8 Hydrochloride
CAS Number:131857-31-3
Molecular Formula:C₁₃H₁₂D₈ClN₃O₃S
Molecular Weight:341.88
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(6R,7R)-7-Amino-3-((1-methylpyrrolidin-1-ium-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate-d8 Hydrochloride is an intermediate for the synthesis of Cefepime-d8 Sulfate (C242759), which is a labelled analogue of Cefepine sulfate, a cephalosporin that has antibacterial effects against Gram-positive and Gram-negative bacteria. Cefepime sulfate is used to treat mild to severe bacterial infections.
References:Neu, H.: Am. J. Med., 100, 68S (1996); Sanders, C.: Clin. Infect. Dis., 17, 369 (1993); Sanders, W., et al.: Clin. Infect. Dis., 23, 454 (1996); Yahav, D., et al.: Lancet Infect. Dis., 7, 338 (2007)
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