(6S)-Hydroxy (S,S)-Palonosetron

Chemical Name:(6S)-Hydroxy (S,S)-Palonosetron
Synonyms:(3aS,6S)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-benz[de]isoquinolin-1-one
CAS Number:848074-08-8
Molecular Formula:C₁₉H₂₄N₂O₂
Molecular Weight:312.41
Category:Research Tools;
Applications:(6S)-Hydroxy (S,S)-Palonosetron is a metabolite of Palonosetron (P165800, HCl salt) which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting.
References:Stoltz, R., et al.: Biopharm. Drug Dispos., 25, 329 (2004)
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