6β-Ethyl-7-keto-obeticholic Acid

Chemical Name:6β-Ethyl-7-keto-obeticholic Acid
Synonyms:(3α,5β,6β)-6-Ethyl-3-hydroxy-7-oxocholan-24-oic Acid; (3α,5β,6β)-6-Ethyl-3-hydroxy-7-oxo-cholan-24-oic Acid
CAS Number:915038-25-4
Molecular Formula:C₂₆H₄₂O₄
Molecular Weight:418.61
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
Applications:6β-Ethyl-7-keto-obeticholic Acid is an intermediate of Obeticholic Acid (E899810). Obeticholic Acid is a derivative of the bile acid Chenodeoxycholic Acid (C291900). Obeticholic Acid is a potent activator of the farnesoid X nuclear receptor which reduces liver fat and fibrosis in animal models of fatty liver disease.
References:Neuschwander-Tetri, B.A., et al.: Lancet., 385, 956 (2015)
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