CAS:635728-49-3|Darunavir Ethanolate

Catalogue Number:D193520
Chemical Name:Darunavir Ethanolate
Synonyms:N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic Acid (3R,3aS,6aR)Hexahydrofuro[2,3-b]furan-3-yl Ester compd. with Ethanol;
CAS Number:635728-49-3
Molecular Formula:C₂₉H₄₃N₃O₈S
Appearance:White to Off-White Solid
Melting Point:98-100°C
Molecular Weight:593.73
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Darunavir Ethanolate (Prezista) is an HIV protease inhibitor. Derivative of Darunavir (D193500), a second generation HIV-1-protease inhibitor
References:Holmstock, N. et al.: Drug Metab. Disp., 40, 1473 (2012); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),
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