CAS:1546918-95-9|1-epi-Darunavir

Catalogue Number:D193505
Chemical Name:1-epi-Darunavir
Synonyms:[(1R,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester
CAS Number:1546918-95-9
Molecular Formula:C₂₇H₃₇N₃O₇S
Appearance:White to Off-White Solid
Melting Point:81-85°C
Molecular Weight:547.66
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Moisture Sensitive
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
Applications:Stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor
References:Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),
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