2-Amino-6,8-dihydroxypurine-15N5

Chemical Name:2-Amino-6,8-dihydroxypurine-15N5
Synonyms:8-Hydroxyguanine-15N5; 2-(Amino-15N)-7,9-dihydro-1H-purine-6,8-dione-1,3,7,9-15N4; 2-Amino-7,9-dihydro-1H-purine-6,8-dione-15N5; 2-Amino-6,8-purinediol-15N5; 8-Hydroxyguanine-15N5; 8-Oxo-7,8-dihydroguanine-15N5; 8-Oxoguanine-15N5; NSC 22720-15N5
CAS Number:1358676-24-0
Molecular Formula:C₅H₅¹⁵N₅O₂
Molecular Weight:172.09
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-Amino-6,8-dihydroxypurine-15N5 is the isotope labelled analog of 2-Amino-6,8-dihydroxypurine (A604921, HCl); an 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase λ.
References:Avkin, S., et al.: Mutat. Res., 510, 81 (2002); Niimi, N., et al.: Biochem., 48, 4239 (2009); Muftuoglu, M., et al.: J. Biol. Chem., 284, 9270 (2009)
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