4-Desmethyl Istradefylline-d3,13C

Chemical Name:4-Desmethyl Istradefylline-d3,13C
Synonyms:(E)-1,3-Diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-1H-purine-2,6-dione-d3, 13C
Alternate CAS #:Unlabelled: 160434-48-0
Molecular Formula:C₁₈¹³CH₁₉D₃N₄O₄
Molecular Weight:374.41
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Isotope labelled 4-Desmethyl Istradefylline is an impurity of Istradefylline (I927000), a selective A(2A) antagonist used in the treatment of Parkinson’s disease. 4-Desmethyl Istradefylline have also been shown to exhibit inhibitory potency towards adenosine A2A receptors and is classified as its an adenosine A2A receptor antagonist.
References:Jorg, M., et al.: Bioorg. Med. Chem. Lett., 23, 3427 (2013);
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