CAS:81-49-2|1-Amino-2,4-dibromo-anthraquinone

Catalogue Number:A604460
Chemical Name:1-Amino-2,4-dibromo-anthraquinone
Synonyms:NSC 3529; 1-Amino-2,4-dibromo-9,10-anthracenedione; 1-Amino-2,4-dibromo-9,10-anthraquinone; 1-Amino-2,4-dibromoanthraquinone;
CAS Number:81-49-2
Molecular Formula:C₁₄H₇Br₂NO₂
Appearance:Red to Dark Red Solid
Melting Point:>220°C (dec.)
Molecular Weight:381.02
Storage:-20°C
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:1-Amino-2,4-dibromo-anthraquinone is a useful compound to study the uPAR·uPA protein-protein interaction (PPI) involved in signaling and proteolytic events that lead to tumor invasion and metastasis. It is also used to evaluate potential renal toxicants based on a relationship between chemical-induced kidney weight gain and kidney histopathology in rats. 1-Amino-2,4-dibromo-anthraquinone is a reagent utilized in copper-catalyzed Ullmann condensation to synthesize anthraquinone derivatives as novel dyes.
References:Malik, E. M., et al.: Dyes Pigm. 131, 33 (2016); Craig, E. A., et al.: J. Appl. Toxicol. 35, 729 (2015); Mani, T., et al.: Bioorg. Med. Chem 21, 2145 (2013)
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