CAS:91366-65-3|4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole

CAS:91366-65-3|4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole

Catalogue Number:A629400
Chemical Name:4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole
Synonyms:7-Fluoro-2,1,3-benzoxadiazole-4-sulfonamide; ABD-F
CAS Number:91366-65-3
Molecular Formula:C₆H₄FN₃O₃S
Appearance:White to Light Yellow Solid
Melting Point:144-146°C
Molecular Weight:217.18
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Fluorescent Reagents; Sulfhydryl Active Reagents;
Applications:A water soluble pH dependent bifunctional fluorogenic reagent for the sensitive and specific detection of protein thiols. ABD-F is highly reactive and specific for protein thiols, and its selectivity is superior to that of other sulfhydryl-reactive fluorophores such as fluorescein maleimide, 5-iodoacetamidofluorescein, 5-I-AEDANS, dansylaziridine, and bimane. Fluorescence: max Abs. l = 385nm, max Em. l = 520nm
References:Hiratsuka., T.,: J. Biol. Chem., 268, 24742 (1993), Treuheit, M.J., et al.: Anal. Biochem., 212, 138 (1993), Takeda., S., et al.: Trans. Mater. Res. Soc. Jpn., 15A, 509 (1994), Tukushima, T., et al.: Biomed. Chromatogr., 9, 10 (1995), Takeda., S., et al.: J. Biochem., 117, 267 (1995)
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