CAS:887256-40-8|5-Amino-2-hydroxy-4′-sulfo[1,1′-biphenyl]-3-carboxylic Acid

Catalogue Number:A629410
Chemical Name:5-Amino-2-hydroxy-4′-sulfo[1,1′-biphenyl]-3-carboxylic Acid
Impurity:Mesalazine EP Impurity P
CAS Number:887256-40-8
Molecular Formula:C₁₃H₁₁NO₆S
Appearance:White to Light Brown Solid
Melting Point:>272°C (dec.)
Molecular Weight:309.29
Storage:-20°C
Solubility:DMSO (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-Amino-2-hydroxy-4′-sulfo[1,1′-biphenyl]-3-carboxylic Acid is the free form of 5-Amino-2-hydroxy-4′-sulfo[1,1′-biphenyl]-3-carboxylic Acid Hydrochloride (A629343), which is the hydrochloride salt of 5-Amino-3-(4-sulfonylphenyl)salicyclic Acid Sodium Salt (A629340), an impurity of mesalamine (M258100) that is the active metabolite of Sulfasalazine (S699084). Anti-inflammatory (gastrointestinal).
References:Friedman, G., et al.: Am. J. Gastroenterol., 81, 141 (1986); Tursi A., Expert Opin. Pharmacother., 6, 69 (2005)
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