CAS:200815-49-2|Arformoterol Tartrate

Catalogue Number:A767505
Chemical Name:Arformoterol Tartrate
Synonyms:N-[2-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]
CAS Number:200815-49-2
Alternate CAS #
Free Base :67346-49-0
Molecular Formula:C₂₃H₃₀N₂O₁₀
Appearance:White to Pale Brown Solid
Melting Point:181-183°C
Molecular Weight:494.49
Storage:4°C, Inert atmosphere
Solubility:DMSO (Slightly, Sonicated), Methanol (Slightly, Heated, Sonicated), Water (Sligh
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Arformoterol Tartrate, can be used in the synthesis of Omeprazole (O635000), which is a proton pump inhibitor, that inhibits gasteric secretion, also used in the treatment of dyspepsia, peptic ulcer disease, etc. It is also the impurity of Esomeprazole Magnesium (E668300), which is the S-form of Omeprazole, and is a gastric proton-pump inhibitor. Also, It can be used for the preparation of olodaterol, a novel inhaled b2-adrenoceptor agonist with a 24h bronchodilatory efficacy.
References:Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998); Stenhoff, H., et al.: J. Chromatogr., 734, 191 (1999), Johnson, D.A., et al.: Expert Opin. Pharmacother., 4, 253 (2003); Bouyssou, T., et al.: Bio. Med. Chem. Lett. 20, 1410, (2010);
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