CAS:368860-21-3|Arimoclomol Citrate

Catalogue Number:A771280
Chemical Name:Arimoclomol Citrate
Synonyms:N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidoyl chloride 1-oxide 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt)
CAS Number:368860-21-3
Molecular Formula:C₁₄H₂₀ClN₃O₃ • C₆H₈O₇
Molecular Weight:313.78 + (192.12)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Arimoclomol is a co-inducer of HSP that acts through heat shock factor 1 (HSF1) in cells undergoing cellular stress. Has therapeutic potential in motor neuron degenerative diseases. Potential treatment for liposomal storage disorders, such as Niemann-Pick disease type C.
References:Kieran, Dairin., et al.: Nature Medicine., 10, 402 (2004); Brown, Ian R., et al.: Ann N Y Acad Sci., 1113, 147 (2007); Traynor, B. J., et al.: Neurology., 67, 20 (2006),
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