CAS:134523-03-8|Atorvastatin Calcium Salt

Catalogue Number:A791750
Chemical Name:Atorvastatin Calcium Salt
Synonyms:(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt; Atorvastatin Hemicalcium; CI 981; Lipitor; Sortis; Tahor; YM 548;
CAS Number:134523-03-8
Alternate CAS #
Free Acid: 134523-00-5
Molecular Formula:C₆₆H₆₈CaF₂N₄O₁₀
Appearance:White to Off-White Solid
Melting Point:>176°C (dec.)
Molecular Weight:1155.34
Storage:-20°C
Solubility:DMSO (Slightly, Heated), Methanol (Sparingly)
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
References:Zhao Y et al. Medicine (Baltimore). 2017 Feb;96(7):e6104.
Wu X et al. Carcinogenesis. 2017 Feb 16
Sepehri Z et al. PLoS One. 2017 Feb 13;12(2):e0172404
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