CAS:222412-87-5|Atorvastatin-d5 Sodium Salt (>90%)

Catalogue Number:A791752
Chemical Name:Atorvastatin-d5 Sodium Salt (>90%)
Synonyms:(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-(phenyl-d5)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Sodium ; Lipitor-d5 Sodium;
CAS Number:222412-87-5
Alternate CAS #
134523-01-6 – unlabelled/ 749193-45-1-free base
Molecular Formula:C₃₃H₂₉D₅FN₂NaO₅
Appearance:Off-White to Pale Brown Solid
Melting Point:198-201°C (dec.)
Molecular Weight:585.65
Storage:-20°C
Solubility:Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A deuterated selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References:Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),
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