CAS:222412-82-0|Atorvastatin-d5 Calcium Salt

Catalogue Number:A791754
Chemical Name:Atorvastatin-d5 Calcium Salt
Synonyms:(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-(phenyl-d5)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt (2:1); Atorvastatin-d5 Hemicalcium;
CAS Number:222412-82-0
Alternate CAS #
Unlabelled: 134523-03-8
Molecular Formula:C₆₆H₅₈D₁₀CaF₂N₄O₁₀
Appearance:White to Pale Brown Solid
Melting Point:>161°C (dec.)
Molecular Weight:1165.42
Storage:-20°C, Inert atmosphere
Solubility:Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:di(Atorvastatin-d5) Calcium Salt is the labeled analogue of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
References:Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)
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