CAS:1105067-88-6|(3S,5S)-Atorvastatin Calcium Salt

Catalogue Number:A791755
Chemical Name:(3S,5S)-Atorvastatin Calcium Salt
Synonyms:(βS,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt; Atorvastatin Hemicalcium; CI 981 Calcium Salt; Lipitor Calcium Salt; Sortis Calcium Salt; Tahor Calcium Salt; YM 548 Calcium Salt; USP Atorvastatin Related Compound E;
Impurity:Atorvastatin Related Compound E
CAS Number:1105067-88-6
Alternate CAS #
Free Acid: 501121-34-2
Molecular Formula:C₆₆H₆₈CaF₂N₄O₁₀
Appearance:White to Off-White Solid
Melting Point:>153ºC (dec.)
Molecular Weight:1155.34
Storage:4°C
Solubility:DMSO (Slightly, Sonicated), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Impuritiy of Atorvaststin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Atorvastatin Related Compound E
References:Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),
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