CAS:74469-00-4|Augmentin

CAS:74469-00-4|Augmentin

Catalogue Number:A794740
Chemical Name:Augmentin
Synonyms:Mixture of Amoxicillin and Potassium Clavulanate (~4:1); Amocla; Amoclan; Amoclav; Amoran; Amox-clav; Amoxicillin-clavulanate Potassium Mixture; Amoxicillin-potassium Clavulanate Mixture; Amoxyclav; Ancla; Augmentan; Augmentin; Augmentin (antibiotic); Augmentin ES 600; Augmentine; Auspilic; BRL 25000; BRL 25000A; BRL 25000G; Clamentin; Clamobit; Clamonex; Clamoxyl; Clavamox; Clavinex; Clavoxilin Plus; Clavulin; Clavumox; Eumetinex; Forcid Solutab; Kmoxilin; Proclav S; Spectramox; Viaclav; Xiclav; co-Amoxyclav; Potassium (2R,5R,Z)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate (2S,5R,6R)-6-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Mixture;
CAS Number:74469-00-4
Alternate CAS #
Free Acid: 79198-29-1
Molecular Formula:4(C₁₆H₁₉N₃O₅S)•(C₈H₈KNO₅)
Appearance:Pale Yellow to Light Beige Solid
Melting Point:>188°C
Molecular Weight:4(365.40) + (237.25)
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Water (Slightly)
Stability
Hygroscopic, Temperature sensitive
Category:Standards; Antibotics;
Applications:Augmentin is a 4:1 mixture of Amoxicillin to Clavulanate which is an enhanced formulation that serves as broad-spectrum antibiotic that is more effective against resistant pathogens. It maintains therapeutically useful concentrations of plasma Amoxicillin for longer periods after dosing.
References:Kaye, C., et al.: Clin. Ther., 23, 578 (2001);
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