CAS:2130853-04-0|Belinostat Acid-d5

Catalogue Number:B131487
Chemical Name:Belinostat Acid-d5
Synonyms:(2E)-3-[3-[(Phenylamino)sulfonyl]phenyl]-2-propenoic Acid-d5; (E)-3-(3-(N-Phenylsulfamoyl)phenyl)acrylic Acid-d5
CAS Number:2130853-04-0
Molecular Formula:C₁₅H₈D₅NO₄S
Molecular Weight:308.36
Category:Standards; Isotopic Labeled Analogues; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Belinostat Acid-d5 is the labelled analogue of Belinostat Acid (B131485), a metabolite of Belinostat (B131400), a novel histone deacetylase 3 selective inhibitor, which protects the β cells from cytokine-induced apoptosis.
References:Chou, D.H., et al.: Chem. Biol., 19, 669 (2012); Hwang, J.J., et al.: Inves. New. Drugs., 30, 1434 (2012); Dizon, D.S., et al.: Gynecol. Oncol., 125, 367 (2012);
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