CAS:1137621-29-4|Belinostat Ethyl Acetate

Catalogue Number:B131488
Chemical Name:Belinostat Ethyl Acetate
Synonyms:(E)-Ethyl 3-(3-(N-Phenylsulfamoyl)phenyl)acrylate
CAS Number:1137621-29-4
Molecular Formula:C₁₇H₁₇NO₄S
Appearance:Light brown solid
Molecular Weight:331.39
Storage:4°C
Solubility:Chloroform-d
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Belinostat Ethyl Acetate is an intermediate in the synthesis of Belinostat Acid (B131485). Belinostat Acid is a metabolite of Belinostat (B131400), a novel histone deacetylase 3 selective inhibitor, which protects the b cells from cytokine-induced apoptosis.
References:Chou, D.H., et al.: Chem. Biol., 19, 669 (2012); Hwang, J.J., et al.: Inves. New. Drugs., 30, 1434 (2012); Dizon, D.S., et al.: Gynecol. Oncol., 125, 367 (2012);
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