ARP 100

Chemical Name:ARP 100
Synonyms:2-[((1,1′-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide
CAS Number:704888-90-4
Molecular Formula:C₁₇H₂₀N₂O₅S
Molecular Weight:364.42
Category:Standards; Enzyme Activators and Inhibitors;
Applications:ARP 100 is a potent, dual inhibitor of MMP-12/MMP-13 targets, which are a family of zinc dependent endopeptidases known to play key roles in extracellular matrix (ECM) breakdown disorders, such as the two main forms of arthritis, rheumatoid arthritis (RA) and osteoarthritis (OA).
References:Santamaria, S.; et al.; Biochem. Pharmacol., 84, 813 (2012)
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