CAS:64544-07-6|Cefuroxime Axetil

Catalogue Number:C248065
Chemical Name:Cefuroxime Axetil
Synonyms:(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 1-(Acetyloxy)ethyl Ester; Altacef; Bioracef; CCI 15641; Cefaks; Cefazine; Ceftin; Cefurax; Cefuroxime 1-Acetoxyethyl Ester; Elobact; Forcef; Oraxim; Zinat; Zinnat;
CAS Number:64544-07-6
Molecular Formula:C₂₀H₂₂N₄O₁₀S
Appearance:White to Pale Yellow Solid
Melting Point:108 – 120°C
Molecular Weight:510.47
Storage:-20°C
Solubility:DMSO (Sparingly), Methanol (Sparingly)
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:It is the 1-(acetyloxy) ethyl ester of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester has a broader spectrum of activity than cephalexin (first-generation) and is widely used to treat respiratory tract infections. Antibacterial.
References:Nguyen, N., et al.: Pharm. Res., 8, 893 (1991), Stoeckel, K., et al.: Antimicrob. Agents Chemother., 42, 2602 (1998), Scott, L., et al.: Drugs, 61, 1455 (2001), Bulitta, J. B., et al.: Antimicrob. Agents Chemother., 53, 3462 (2009);
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