CAS:123458-61-7|Δ2-Cefuroxime Axetil(Cefuroxime Axetil Delta-3 Isomer)

Catalogue Number:C248070
Chemical Name:Δ2-Cefuroxime Axetil(Cefuroxime Axetil Delta-3 Isomer)
Synonyms:(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic Acid 1-(Acetyloxy)ethyl Ester; Cefuroxime Axetil EP Impurity A
Impurity:Cefuroxime Axetil EP Impurity A
CAS Number:123458-61-7
Molecular Formula:C₂₀H₂₂N₄O₁₀S
Appearance:White to Pale Yellow Solid
Melting Point:64-71°C
Molecular Weight:510.47
Storage:-20°C
Solubility:DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Sparingly)
Stability
Hygroscopic
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Δ2-Cefuroxime Axetil (Cefuroxime Axetil EP Impurity A) is an oral prodrug of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester is applied in therapy as a mixture of the R and S diastereoisomers.
References:Nguyen, N., et al.: Pharm. Res., 8, 893 (1991),
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